EFFECTS OF SINGLE NUCLEOTIDE POLYMORPHISMS ON HUMAN N-ACETYLTRANSFERASE 2 STRUCTURE AND DYNAMICS BY MOLECULAR DYNAMICS SIMULATION.

Effects of single nucleotide polymorphisms on human N-acetyltransferase 2 structure and dynamics by molecular dynamics simulation.

BACKGROUND: Arylamine N-acetyltransferase 2 (NAT2) is an important catalytic enzyme that metabolizes the carcinogenic arylamines, hydrazine drugs and chemicals.This enzyme is highly polymorphic in different human populations.Several polymorphisms of NAT2, including the single amino acid substitutions Enhanced Photocatalytic Degradation Activity of

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Measurement and prevalence of sexual harassment in low- and middle-income countries: a systematic review and meta-analysis

Objectives We synthesise evidence on sexual harassment from studies in low-income and middle-income countries (LMICs) to estimate its prevalence and conduct a meta-analysis of the association between sexual harassment and depressive symptoms.Methods We searched eight databases.We included peer-reviewed studies published in English from 1990 until A

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Deconvolution effect of near-fault earthquake ground motions on stochastic dynamic response of tunnel-soil deposit interaction systems

The deconvolution effect of the near-fault earthquake ground motions on the stochastic dynamic response of tunnel-soil deposit interaction systems are investigated by using the finite THE EFFECTS OF PANDEMIC DISEASES ON THE WORLD ECONOMY element method.Two different earthquake input mechanisms are used to consider the deconvolution effects in the a

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